Pain Relievers

General Health

Pain relievers (analgesics) are among the most-used medicines worldwide. The three main over-the-counter groups — paracetamol, NSAIDs, and combination products — each have different uses, risks and cautions.

Also known as: Analgesics, Pain killers, Pain medicines

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About Pain Relievers

About this summary: Written by Swasthya Plus for Indian readers, using MedlinePlus, National Library of Medicine as a reference source. For personal guidance, please consult a qualified Health Expert.

Pain relievers (analgesics) are among the most-used medicines worldwide. The three main over-the-counter groups — paracetamol, NSAIDs, and combination products — each have different uses, risks and cautions. This page is a general guide; ask a Health Expert if pain is severe or unusual.

Paracetamol (acetaminophen)

  • First-choice for most mild-to-moderate pain and fever.
  • Safer on the stomach and kidneys than NSAIDs; safer in children.
  • Overdose damages the liver — stay within the recommended daily dose shown on the pack; avoid alcohol while taking it.
  • Check combination products — many cold/flu tablets already contain it; adding separate paracetamol can accidentally double the dose.

NSAIDs (anti-inflammatory painkillers)

  • Effective for pain with inflammation — arthritis, injuries, menstrual cramps, dental pain.
  • Take with food to reduce stomach irritation.
  • Risks: stomach ulcers and bleeding, kidney damage, higher blood pressure, and in heart-failure or chronic kidney disease they can be dangerous.
  • Use at the lowest effective dose for the shortest time.
  • Avoid NSAIDs in suspected dengue — they raise bleeding risk. Use paracetamol instead.
  • Avoid in later pregnancy unless a Health Expert advises.

Opioids (stronger prescription painkillers)

  • Reserved for severe pain (post-surgery, cancer, major injury).
  • Always on prescription.
  • Constipation, drowsiness, nausea are common.
  • Long-term use risks dependence and tolerance — short courses only.

Practical India notes

  • Many pharmacy-sold "body pain" combinations mix painkillers, caffeine and sometimes other drugs — taking them for weeks can quietly cause kidney and stomach harm.
  • Never self-prescribe painkillers for more than a few days for persistent pain — see a Health Expert to find the cause.
  • Topical pain gels are a low-risk alternative for localised muscle/joint pain.
  • Unregulated ayurvedic "pain relief" products have been found containing hidden steroids or NSAIDs — unusually rapid relief from an unbranded product is a warning sign.

Reference source: MedlinePlus, National Library of Medicine